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diagnosis endocrinology differential causes disease hyperthyroid hypothyroid hypothyroidism treatment autoimmune disorders drugs highthyroid interpretation iodine lowthyroid medications pharmacology pmr polymyalgia
Thyroid Disorders - Differential Diagnosis Algorithm Hypothyroidism: • Hasimoto’s • Radioactive Iodine • Hypopituitarism • Iodine
Thyroid Disorders ... Differential Diagnosis Algorithm ... Hypothyroidism ... : • Graves’ ... @AmyChung #Thyroid
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Approach to Thyroid ... symmetrically enlarged thyroid ... ophthalmopathy → Graves ... → Radioactive Iodine ... #algorithm #diagnosis
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
Hyperthyroidism ... Radioactive iodine ... concern for nodular thyroid ... Graves disease – ... workup choices AND management
Graves' Disease Treatment Thionamides (mainly methimazole) • Chance of remission in up to 2 years • No
Graves' Disease ... 2 years • No thyroid ... cost Radioactive Iodine ... mendesthiagob #Graves ... Disease #Treatment #Management
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm • Secondary Hyperthyroidism (↑↔TSH,
Diagnosis and Workup Algorithm ... Radioactive Iodine ... High Uptake: • Graves ... • Exogenous thyroid ... Differential #Diagnosis #Algorithm
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake Reduced uptake: • Thyroiditis • Exogenous
Differentiation of Causes of Hyperthyroidism ... loading • Ectopic thyroid ... increased uptake: • Graves ... disease • Excess thyroid-stimulating ... differential #diagnosis #hyperthyroidism
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism ... diffuse goiter (Graves ... Toxicosis • Iodine ... antibodies (TRAb) if Graves ... Thionamide - Iodine
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
Disease Hyperthyroidism ... : • Graves disease ... uptake Hypothyroidism ... positive • Ablative hypothyroidism ... • Infantile hypothyroidism
Graves Hyperthyroidism - Diagnosis and Management Algorithm Low TSH -> TSH-R-Ab+ -> Graves' Hyperthyroidism doi: 10.1210/clinem/dgaa646 #Graves #Disease #Hyperthyroidism
Graves Hyperthyroidism ... Diagnosis and Management ... Algorithm Low TSH ... ' Hyperthyroidism ... #Management #Algorithm
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm Beta-Blockers • Decreases sympathetic hyperactivity • Partially blocks peripheral conversion
Pharmaceutical Management ... of Hyperthyroidism ... • Teratogenic Iodine ... autoimmune process in Graves ... #ThyroidStorm #Management
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