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management oncology rheumatology differential hepatology dermatology physicalexam anemia cirrhosis classification hemophagocytic hepatopulmonary hlh lymphohistiocytosis neurology treatment agglutinin algorithm ana antibodies
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
as jaundice on clinical ... examination; nonspecific symptoms ... Newborn: associated ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Signs/Symptoms ... Infertility • Decr Bone ... pathophysiology #peds ... #pediatrics
Staphylococcal Scalded Skin Syndrome (SSSS) A 5-year-old girl presents to the ED with a rash that started
respiratory infection one ... Scalded #Skin #Syndrome ... #SSSS #Clinical ... #Photo #Peds #Pediatrics ... #Dermatology
Osteosarcoma Most common primary malignant bone tumor in children Most Common Sites of Involvement: 1. Distal femur
proximal femur Clinical ... injury • Systemic symptoms ... #Osteosarcoma #Diagnosis ... Features #Oncology #Peds ... #Pediatrics #BonyTumor
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... mutations - BMPR2 (bone ... hypertension of the newborn ... multifactorial mechanisms Hematologic ... Classification #Diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... infection, autoimmune disorder ... Viral Infection Clinical ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... are a group of disorders ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... development of skin symptoms ... , breast CA - Hematologic ... skin lesions by one ... #diagnosis #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... lymphoproliferative disorders ... • Richter’s Syndrome ... workup #oncology #hematology
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