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Thyroid gland SIH TRH Follicular cells Capillaries HVL TSH T4 Thyroxine (tetraiodothyronine) 5 -lodinase Colloid #Triiodothyronine #lodine uptake, hormone synthesis and secretion see Fig. 95つ Metabolism, growth, maturation, etc.
tetraiodothyronine) 5 -lodinase ... Colloid #Triiodothyronine ... #lodine uptake
lodine deficiency Food lodine excess Stress Catecholamines Estrogens Carrier defect Nat TRH Hypothalamic lesion Dopamine Somatostatin Glucocorticoids TSH Pituitary insufficiency Autoimmune disease TSI Peroxidase Peroxidase deficiency ОН TG DIT Coupling ОН Cell proliferation Thyroglobulin TG Cell damage by tumor, inflammation, etc. Proteolysis Goiter TG MIT ОН Defective conversion T4 TG TG Storage Colloid Genetic defect,
lodine deficiency ... Food lodine excess ... TG Storage Colloid ... Genetic defect, #lodine
1 Thyroglobulin synthesis Amino acids Carbohydrates Peptides Ribosomes Capillary Endoplasmic reticulum Follicular cell 2 lodine uptake, hormone synthesis, and storage SCN- C104 NOZ Г pool Nat symport (NIS) TSH Nat 3 Hormone secretion Primary
Follicular cell 2 lodine ... Golgi apparatus Colloid
REBEL Review 70: Fluid Composition - Colloids and Crystalloids Colloids: Dextran, Gelatin - Crystalloids: Normal Saline, Ringer's
Composition - Colloids ... Crystalloids Colloids ... Osmolarity Colloid ... #crystalloids #colloids
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake Reduced uptake: • Thyroiditis • Exogenous
thyroxine • Iodine ... loading • Ectopic ... #radioactive #iodine
IV Fluids - Comparison Table Fluid - pH - Osm - Na - Cl - Other •
Plasma-lyte • Colloids
Amiodarone induced thyroid changes Histopath: Remarkably enlarged follicles, distended with colloid, without scalloping, and lined by flattened
distended with colloid ... those living in iodine-depleted ... by amiodarone's iodine
Hypotension in Anesthesiology - Differential Diagnosis and Management Initial checklist: - Verify BP (e.g. surgeon
Give colloids
Thyroid Disorders - Differential Diagnosis Algorithm Hypothyroidism: • Hasimoto’s • Radioactive Iodine • Hypopituitarism • Iodine
• Radioactive Iodine ... Hypopituitarism • Iodine
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm • Secondary Hyperthyroidism (↑↔TSH,
Radioactive Iodine ... disease • Low iodine ... goiter Radioactive Iodine ... • Thyroiditis, Iodine
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