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differential causes management workup nephrology hematology ddxof evaluation peds pulmonary em cardiology pediatrics endocrinology dermatology neurology treatment gastroenterology im obgyn
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... Deficiency Testing Algorithm ... ARUPLabs #C1INH #Complement ... Deficiency #Testing #Algorithm ... #allergy #diagnosis
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Hypersensitivity #Allergy ... #Allergic #Reactions ... Classification #Diagnosis
Allergic Reaction Classification Type 1 reaction: Acute anaphylactic reaction Type 2 reaction: Cytotoxic reaction Type 3 reaction: Immune complex Type
Allergic Reaction ... delayed reaction #Allergic ... Classification #Types #allergy ... #diagnosis
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... #Diagnosis #Reactions
Pediatric Anaphylaxis Algorithm #Anaphylaxis #Algorithm #Pediatrics #Peds #Allergy
Pediatric Anaphylaxis Algorithm ... #Anaphylaxis #Algorithm ... Pediatrics #Peds #Allergy
Algorithm for Suspected Penicillin Allergy in Patients Undergoing Surgery • Cephalosporins may be prescribed to patients
Algorithm for Suspected ... Penicillin Allergy ... decision support algorithm ... are diagnosed as ... #Surgery #Algorithm
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Classification Diagnosis ... Angioedema: • Acute allergic ... exposure • Non-allergic ... or avoiding the allergen ... Classification #Types #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... #differential #diagnosis ... #algorithm #rheumatology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
staining (lg + complement ... MGPN • Complement ... of alternative complement ... MPGN without complement ... MPGN #nephrology #diagnosis
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... reactions #types #allergy
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