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diagnosis differential comparison management pharmacology algorithm dermatology clinical rheumatology cardiology classification treatment hematology radiology lupus nephrology medications pulmonary sle pathophysiology
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... they activate complement ... Systemic lupus erythematosus ... types #allergy #table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... Systemic Lupus Erythematosus ... 80% - Low complement ... sle #comparison #table
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Systemic Lupus Erythematosus ... Hypocomplementemia #Low #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Positive in 60-80% of cases ... 80% - Low complement ... lupus #Systemic #Erythematosus
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... differential #diagnosis #causes
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Systemic #Lupus #Erythematosus
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Antibody/DAT+ - Complement ... Differential #Diagnosis #Causes
Pustular Skin Rash - Differential Diagnosis Algorithm Pruritic / Scaly / Erythematous lesions, usually poorly demarcated Acneiform -
Pruritic / Scaly / Erythematous ... demarcated Acneiform - Erythematous ... thick honey-yellow crusts ... - "Beefy red" erythematous ... Diagnosis #Algorithm #causes
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... systemic lupus erythematosus ... Diagnosis #Reactions #Table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Systemic Lupus Erythematosus ... anti-Smith Ab, low complements ... cutaneous lupus erythematosus ... (ACLE) • Erythematous ... RNP antibodies, Complement
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