5 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Idiopathic • Normal ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... - (C-ANCA) pattern ... - (P-ANCA) pattern ... against MPO • Complement ... #rheumatology #classification
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... protein receptor type ... and obstructive pattern ... neurofibromatosis, vasculitis ... #Diagnosis #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... Kikuchi disease • Type-I ... RNP antibodies, Complement
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney function • Abnormal ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated