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diagnosis hypersensitivity reactions rheumatology types comparison differential erythematosus lupus management sle allergic bloodstream catheter coccidioidomycosis crbsi criteria definitions diseases eosinophilia
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... , seasonal hay fever ... Complement activation ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... peanuts), Hay fever ... , Urticaria, Allergic ... complexes • Ex: Systemic ... #Types #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Anaphylaxis, Hay fever ... they activate complement ... glomerulonephritis, Systemic ... #table #classification
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
initiation of smoking; Fever ... loss, malaise • Allergic ... brown sputum, fever ... , hemoptysis; +systemic ... diagnosis #comparison #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Constitutional domain: Fever ... anticoagulant • Complement ... Criteria #SLE #Systemic
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
infection - Management Algorithm ... weeks of tailored systemic ... • Persistent fever ... • Persistent fever ... infection #Management #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... central nervous system ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... to: Arthritis, Fever
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
known as valley fever ... the lymphatic system ... Central nervous system ... analysis using complement ... TREATMENT: Clinically stable
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