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diagnosis rheumatology lupus management allergy comparison criteria ddxof differential erythematosus hypersensitivity peds reactions systemic vasculitis abpa allergic aspergillosis bronchopulmonary causes
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... Complement activation ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Anaphylaxis, Hay fever ... they activate complement ... #allergy #table ... #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... cutaneous-DIL • Evolution ... 80% - Low complement ... • Evolution: ... #comparison #table
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Types: • Type ... • Low serum C4 complement ... erythematosus (SLE ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
uncharacterized fevers ... Consider BCx, CSF evaluation ... presentation Urinalysis: LE ... Diagnosis #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... to: Arthritis, Fever
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
Differential Diagnosis Algorithm ... Conditions: • Fever ... Vasculopathy (SLE ... , Type 1 diabetes ... Differential #Diagnosis #Algorithm
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
production - Can see ... • Low grade fever ... WHAT CAN YOU SEE ... ON LABORATORY EVALUATION ... • Immediate type-skin
Le Fort Fractures (LFF) are fractures of the mid face. They collectively involve separation of all
Le Fort Fractures ... 3 lines to aid evaluation ... LeFort #Fractures #Types ... #Classification
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