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diagnosis rheumatology lupus allergy comparison erythematosus hypersensitivity reactions vasculitis abpa allergic aspergillosis bloodstream bronchopulmonary catheter clinicopathology coccidioidomycosis crbsi criteria cryoglobulinemia
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... , seasonal hay fever ... Complement activation ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Anaphylaxis, Hay fever ... glomerulonephritis, Systemic ... #allergy #table ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... • Low serum C4 complement ... erythematosus (SLE ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Constitutional domain: Fever ... anticoagulant • Complement ... #Criteria #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... months to years) Systemic ... 80% - Low complement ... Usual therapeutic management ... #comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
Algorithm • Temperature ... weeks of tailored systemic ... • Persistent fever ... • Persistent fever ... #Algorithm #CRBSI
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
• Low grade fever ... WHAT CAN YOU SEE ... • Immediate type-skin ... • Systemic corticosteroids ... pulmonary #diagnosis #management
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... event, follow ACC algorithm ... Risk Stratify Type ... What is the type ... medical and surgical management
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