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diagnosis rheumatology differential sle vasculitis allergy causes comparison erythematosus hypersensitivity potassium reactions renal systemic champs clinicopathology criteria cryoglobulinemia cryoglobulins druginduced
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification Algorithm ... #Lupus #Nephritis ... #Classification ... #differential #types
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... , and systemic lupus ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... they activate complement ... glomerulonephritis, Systemic lupus ... #allergy #table ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... anticoagulant • Complement ... C3 or low C4, Low ... C3 and low C4 ... #EULARACR #Classification
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
glomerulonephritis, type ... 1 (50%-80%), type ... S - Systemic Lupus ... Hypocomplementemia #Low ... #Complement #CHAMPS
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low ... Complement: Post-strep ... GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
tubular acidosis (Types ... and 2, but not type ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... factor level • Low ... serum C4 complement ... (e.g. systemic lupus ... #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... 60-80% - Low ... complement - 50 ... sle #comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... , lymphopenia, low
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