14 results
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... Diagnosis #Management #EM ... FebrileSeizure #Fever ... #Workup #Simple ... #Complex
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... walls Immune-Complex ... staining (lg + complement ... MGPN • Complement ... immune deposits on EM
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tracts Immune Complex ... - Skin, glomeruli ... : - Kidneys: glomerular ... : • Fevers • ... against MPO • Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
immunofluorescence Immune Complex ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... ANCA-positive vasculitis ... ANCA-negative vasculitis ... Cryoglobulinemia) • Immune Complex ... sclerosis • Anti-Glomerular
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... Rash - Diagnostic Algorithm ... Secondary syphilis, EM ... Parvovirus B19 (PPGSS), Vasculitis ... Febrile #Diagnosis #Algorithm
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... or alternative complement ... for ANCA-related vasculitis ... #testing #workup
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... petechiae/purpura with fever ... petechiae/purpura with fever ... petechiae require complete
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... Red Flags: • Fever ... deficiency Work ... Up: • Complete
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... bartonella (oroya fever ... Differential #Diagnosis #Algorithm ... #workup #hematology