549 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... metformin binds to complexes ... Toxicology #Diagnosis #Management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Diagnosis and Management ... decreased reflexes Pathophysiology ... Mycobacterium tuberculosis complex ... smear microscopy Management ... TB #Diagnosis #Management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... binds heparin-PF4 complex ... Management: • ... diagnosis and management
Approach to ECGs - VT vs. SVT - Wide Tachycardias
DDx = VT vs. SVT with BBB
All
VT: - No RS complexes ... - Very broad complexes ... produce a hybrid complex ... onset of the QRS complex ... S-wave - RSR' complexes
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... walking to nearly complete ... Syndrome #diagnosis #management
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... antigen-surface complex ... against these complexes ... or the entire complex ... Allergy #Immunology #pathophysiology
Premature atrial complex (PAC) - ECG Recognition
 • Prematurity and altered P wave morphology.
 • P
Premature atrial complex ... premature junctional complex ... premature #atrial #complexes
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune Complex ... > Incr Immune Complex ... Vasculitis #HUV #Pathophysiology
VT versus SVT with Aberration - Interpretation Cheat Sheet

Features favouring VT
● Absence of typical RBBB or
dissociation (P and QRS complexes ... beats (hybrid complex ... negative (QS) complexes
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
walking to nearly complete ... the underlying pathophysiology ... Syndrome #diagnosis #management