18 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Cathepsin G release → vascular ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
postpartum): • Initial symptoms ... vomiting, abdominal pain ... infiltration) Differential ... Diagnosis: Viral ... #management #pathophysiology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... constitutional symptoms ... #Differential # ... Diagnosis #MSK #
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... osteopetrosis, avascular ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
chest/abd/back pain ... Marfans, EDS ... Pulse deficit/differential ... Aortic #Dissection #diagnosis ... #management #vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... Behcet disease) Differential ... Nonsurgical abdominal pain ... #management #signs ... #symptoms #rheumatology
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
Clinical Signs/Symptoms ... Bleeding, abdominal pain ... • Should be on differential ... Pathophysiology: ... #vascular
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... cortical lesions • Vascular ... Reversible course Differential ... #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... claudication: pain ... chews, not just pain ... them, but urgent rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... pulse deficits vascular ... tract: Abdominal pain ... • Progressive symptoms ... #Diagnosis #Rheumatology