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hematology differential algorithm macrocytic oncology rheumatology aafp approach arthritis calculation chronic cll criticalcare erythematosus folicacid gap globulin homocysteine index joint
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... RBC = red blood cell ... by ordering a peripheral ... #Diagnosis #Macrocytosis ... #VitaminB12 #Folate
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... cytometry • Peripheral ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Mean corpuscular (cell ... immature RBCs) in peripheral ... High in acute blood ... #Workup #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
released in the peripheral ... , Vitamin B12, Folate ... Index > 3: • Acute ... defects (e.g. sickle cell ... #differential #diagnosis
Shock - Diagnosis and Management Summary • Hypotension: SBP<90, SBP drop >40, MAP<65 (Normotension, HTN possible
Shock - Diagnosis ... bore (18-gauge) peripheral ... support - Call ... and Survey 4) Workup ... - Pulmonary >> Acute
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... Send for cell count ... syphilis, alcohol - peripheral ... = Worry about late ... rheumatology #approach #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... Mononeuritis Multiplex • Peripheral ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
ridging around the periphery ... Diagnosis? ... • No CRAB - no anemia ... Evaluation? ... #Workup #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... myeloma • Plasma cell ... anemia • Other ... #differential #diagnosis
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