28 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... #geriatrics #diagnosis ... #signs #symptoms
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
and workup ... 1) Clinical diagnosis ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... MNCD #Dementia #Differential
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Diagnosis Baseline ... clinical context and signs ... • Cardio-renal syndrome ... #Injury #AKI #Workup
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... of normal leg reflexes ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Locked-in syndrome ... • Mutism Pathophysiology ... • Examine for signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
and Management ... cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
causes such as reflex ... carotid sinus syndrome ... syncope (ruling out differential ... further guide management ... orthostatic vital sign
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
hyperthermia crisis (late sign ... • Serotonin syndrome ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential ... Diagnosis Approach ... hypertension and signs ... renal bruit or signs