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diagnosis hematology oncology syndrome lymphoma behcet chronic classification cll comparison differentiation erythematosus hemophagocytic immune inflammatory iris leukemia lupus lymphocytic lymphohistiocytosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... symptoms - Pel-Ebstein ... involvement Differential ... Malignancies (eg CML, ALL ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Hemopathies+++: Hodgkin ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... Transform to DLBCL, PML ... leukemia, Hodgkin
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ) Differential Diagnosis ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... erythematosus (ACLE ... permanent alopecia Differential ... La, anti-Jo-1, SCL ... cyclophosphamide) • Hodgkin
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML ... #Diagnosis #Management
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