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diagnosis differential hematology management signs vasculitis apml arthritis behcet classification cryofibrinogenemia differentiation disease erythematosus lupus monoclonal paraproteinemias polychondritis ra relapsing
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... meningitis), MCC CNS symptoms ... disease (SVC/IVC occlusion ... management #signs #symptoms ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... pulmonary emboli, and ocular ... thrombi including retinal ... and/or venous occlusions ... Antiphospholipid syndrome
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... Anaphylaxis, Acute Renal ... Differentiation #Syndrome ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ulcers, cutaneous, ocular ... • Cogan Syndrome ... reactions, and vaso-occlusive ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... reactions, and vaso-occlusive ... Presentation: Systemic Symptoms ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Non-autoimmune rheumatologic ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Arthritis - Signs and Symptoms ... • Ocular: Keratoconjunctivitis ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... chondritis • Ocular ... Heart failure • Renal ... Polychondritis #rheumatology
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