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diagnosis hematology oncology chronic cll differentiation leukemia lymphocytic management workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... Cathepsin G release → vascular ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Physical Exam/Signs ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
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