39 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tumor • Motor Nerves ... Guillain-Barre syndrome ... #differential #diagnosis ... #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... • Pain: Due to nerve ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs and Symptoms ... over time) • Weakness ... Radiculopathy #MSK #diagnosis ... #signs #symptoms ... #pathophysiology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progressive muscle weakness ... Progression of weakness ... , Mild sensory symptoms ... signs, Cranial nerve ... #neurology #neuropathy
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis ... #neurology
CN III Palsy - Oculomotor Nerve
 • Ptosis: Loss of innervation of the levator palpebrae superior.
Palsy - Oculomotor Nerve ... comparison to Horner's syndrome ... Extraocular Muscle Weakness ... #Cranial #neurology ... #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... anesthesia. leg weakness ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Complications: • Weakness ... damage to sacral nerves ... #MSK #pathophysiology ... #diagnosis #symptoms
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
- Differential Diagnosis ... Consciousness • Cranial Nerve ... Brown-Sequard Syndrome ... ipsilateral to weakness ... #Hemiplegia #Neurology
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
onset of limb weakness ... spinal cord and nerve ... tubercles • Limb weakness ... Reconstitution Inflammatory Syndrome ... #Tuberculosis #diagnosis