35 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Clinical Manifestations ... #Diagnosis #Management ... #Hematology #SickleCell ... Workup #Algorithm #Ddxof
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
and Evaluation ... Identification of onset (acute ... , liver, renal disease ... #EM #IM #Nephro ... Differential #Algorithm #Ddxof
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... Consider BCx, CSF evaluation ... presentation Urinalysis: LE ... #Peds #EM #Classification ... #Ddxof
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - APLS • Acute ... Associated - SLE ... mountain spotted fever ... #hematology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... of SLEEvolution ... : Chronic disease ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... of SLEEvolution ... : Chronic disease ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
: fever +++, hepatosplenomegaly ... : SLE+++, Adult-onset ... Drugs, Unknown cause ... inhibitors under evaluation ... #management #treatment
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... arthritis - SLE ... Reactive Syndrome - Acute
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Lutzomyia verrucarum Clinical ... Nodular → Mular DIAGNOSIS ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... Classification: • Acute ... Differential Diagnosis ... to: Arthritis, Fever