12 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , deficiency anemia ... Vasculitides, IBD, Celiac disease ... Diagnosis #Algorithm #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... ), RA, crystal disease ... Inflammatory, crystalline disease ... #rheumatology # ... approach #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... changes), high MCV anemia ... - Bone marrow evaluation ... #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Disease: • Pain ... disease must be ... Arthritis: • Acute ... #Pain #MSK #rheumatology ... #approach #workup
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... hallmark for the disease ... result in severe anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Arthritis: • Joint ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... bone pain, fever, joint ... - infiltrates (anemia ... #Leukemia #Hematology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... • An evaluation ... Also consider an evaluation ... • Normocytic anemia ... Diagnosis #Management #Rheumatology