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diagnosis differential hepatology ascites causes albumin chemistry chronic failure gastroenterology globulin gradient hypertension interpretation lfts management portal protein proteingap rvalue
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... #Acute #Chronic ... #Cirrhosis #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... fibrosis - Acute ... fatty liver of ... #differential #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
HTN: ascites (SAAG ... /acute hepatitis ... • Infiltrative diseases ... sarcoidosis) • Liver ... Veno-occlusive disease
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Albumin Gradient (SAAG ... >1.1 g/dl): - Cirrhosis ... ascites - Massive liver ... - Acute fatty ... liver of pregnancy
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... ALF): • Liver ... : > 1 • Acute
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Viral infections (acute ... disease: Cirrhosis ... inflammation (acute
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