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diagnosis differential causes lfts management primary acute biliary cholangitis gastroenterology injury abnormal ascites chemistry chronic disorders enzymes failure gap globulin
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... disease, liver ... #Acute #Chronic ... #Cirrhosis #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... of autoimmune disease ... Liver biopsy findings ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... /Liver failure ... or higher • Liver ... #diagnosis #workup ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Syndrome, Celiac Disease ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... disease, decrease ... disease), HBsAg ... - Bone marrow evaluation ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
• CIRRHOSIS - ... indications for liver ... and end-stage liver ... clinical trial evaluation ... management #summary #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALF): • Liver ... of cholestatic disease ... disease: > 2 ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Differential Diagnosis Algorithm ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... #Hepatology #causes
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