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diagnosis hepatology differential management acute chemistry chronic failure gap gastroenterology globulin indications interpretation lfts protein proteingap rvalue transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... disease, liver ... Injury (DILI) ... #Cirrhosis #Hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Indications for Albumin ... Management of Cirrhosis ... ascites removed • Acute ... kidney injury ( ... #treatment #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALF): • Liver ... of cholestatic disease ... Production: • Albumin ... disease: > 2 ... hepatitis: < 1 • Cirrhosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Total Protein - Albumin ... > 4) Work-up ... first step in evaluation ... Sarcoidosis) • Liver ... disease: Cirrhosis
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