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diagnosis rheumatology management hematology differential druginduced erythematosus activation causes chronic classification cll comparison disease gap globulin high hyperkalemia laboratory leukemia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... • Immunologic Workup ... months to years) Systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... versus DIL • ... • Immunologic Workup ... life-threatening • Treatment ... #lupus #Systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... with leukopenia, anemia ... Treatment: • Corticosteroids
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... #Systemic #Lupus
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... • Immunologic Workup ... • Evolution: ... #diagnosis #treatment
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... lupus erythematosus ... the presence of anemia ... Screening Tests for Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
PMR) is a common systemic ... presents with an acute ... • An evaluation ... for giant cell arteritis ... • Normocytic anemia
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
lupus erythematosus ... (SLE), sickle cell ... anemia, obstructive ... uropathy, post-acute ... Acute oliguric kidney
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... globulin gap (>4 g/dL ... first step in evaluation ... (RA, Temporal arteritis ... Thalassemia, Sickle cell anemia
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