25 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... - Bone marrow evaluation ... #Differential #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... during medical evaluation ... /µL Workup • Screen ... glucocorticoid treatment ... #Algorithm #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... Hemoglobinopathies (e.g. sickle cell ... #differential #
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Infectious: • Acute ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... Iron deficiency anemia
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
can indicate disease ... lymphoproliferative disorders ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... blood count with differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
diagnosis and treatment ... Inflammatory causes ... Cogan syndrome • Acute ... syndrome • Systemic lupus ... optica spectrum disorder
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Angioimmunoblastic T-cell ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor and lupus ... • Warfarin • Acute ... discern these causes ... • Acute DIC •
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential ... Approach (when evaluation ... Renal parenchymal disease ... #causes #Differential