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diagnosis hematology oncology management mds algorithm cancer chronic cll differential gap globulin leukemia lymphocytic myelodysplasia plasmacytoma pmr polymyalgia protein proteingap
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... marrow studies Treatment ... Immunosuppressive treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... Allogeneic stem cell
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... • An evaluation ... for giant cell ... • Normocytic anemia ... TREATMENT: • The
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic ... syndromes current treatment ... to acute myeloid ... disease tolerate anemia ... with repeated red cell
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • No CRAB - no anemia ... Diagnostic Evaluation ... Bone marrow Treatment ... Oncology #Diagnosis #Workup
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... myeloma • Plasma cell ... anemia • Other ... inflammation (acute
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