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diagnosis oncology rheumatology chronic cll leukemia lymphocytic syndrome classification disease hemeonc hemophagocytic hlh hodgkins igg4 leukostasis lymphohistiocytosis lymphoma lysis mds
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... cells can infiltrate ... smear: Smudge cells ... or basket cells ... • Neutropenia, anemia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
) - Summary Overview ... lymphocytes, smudge cells ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
fever - ACS, AKI ... , acute limb ischemia ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
hypergammaglobulinemia, ↑ acute ... increased IgG4+ cells ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... Summary WHAT ... presents with an acute ... for giant cell ... • Normocytic anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
arises from plasma cells ... from the plasma cells ... monoclonal plasma cells ... clonal plasma cells ... #Hematology
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