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rheumatology lupus druginduced summary treatment algorithm b12 cobalamin comparison conjugated differential em erythematosus gi hemophagocytic hlh hyperbilirubinemia indirect jaundice lymphohistiocytosis
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Algorithm #Diagnosis ... #Management #EM ... #IM #GI #Jaundice ... #Algorithm #Direct ... #Unconjugated #Ddxof
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, SCLE-DIL (terbinafine ... • Immunologic Workup ... • Immunologic Workup ... of SLE • Evolution ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
versus DIL • ... • Immunologic Workup ... : - ANA > ... of SLE • Evolution ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... Autoimmune diseases: SLE ... Cellular immune deficiency ... inhibitors under evaluation ... #management #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... • Immunologic Workup ... : - ANA > ... diagnosis #treatment ... #management
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... : • Vit B12 - aka ... total body stores Evaluation ... , can consider IM ... #diagnosis #management
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