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diagnosis differential management lupus druginduced algorithm anemia bleeding bruising comparison dermatology erythematosus gap globulin hemolytic hemostasis mds myelodysplasia myelodysplastic nonpalpable
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... (e.g., SLE), anti-phospholipid ... - Bone marrow evaluation ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
PURPURA: Platelet ... Splenomegaly - CTD (SLE ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, SCLE-DIL (terbinafine ... • Immunologic Workup ... : - ANA > ... • Immunologic Workup ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
versus DIL • ... • Immunologic Workup ... : - ANA > ... • Evolution: ... Management #Summary #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
genotypes): SS, SC, SE ... with or without platelet ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... administration, evaluation ... discern these causes ... Differential #Diagnosis #Hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... • Immunologic Workup ... : - ANA > ... • Evolution: ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Disorders • Nutritional ... Workup: • Complete ... Syndromes #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... Large vessels (aorta ... such as: • SLE ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology
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