12 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the ... Evaluation and ... Diagnosis #Management #Hematology ... Manifestations #Workup ... #Algorithm #Ddxof
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies (ANA ... ) ANA or Anti-NucIear ... Rheumatic Diseases ... • Rheumatic Diseases ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... Diseases: • Homogeneous ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... : - ANA > ... management of SLE • Evolution ... : Chronic disease ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : - ANA > ... : - ANA > ... : Chronic disease ... comparison #table #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... vasculitis, rheumatoid ... Serositis Labs: • ANA ... antibodies • (-) ANA ... Erythematosus #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Antinuclear antibody (ANA ... thus, a negative ANA ... #Disease #Rheumatoid ... diagnosis #testing #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Workup History ... PT, aPTT(liver disease ... function test, ANA ... - Bone marrow evaluation ... #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... aorta • Head ... antinuclear antibodies, rheumatoid ... management #phenotypes #workup ... #treatment #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Others: • Lupus ... • GCA: - Aorta ... Diagnosis: Systemic rheumatic ... LFT • ESR • ANA ... differential #diagnosis #rheumatology