9 results
diagnosis rheumatology hematology druginduced treatment activation bleeding bruising comparison cvid differential erythematosus hemophagocytic hemostasis hlh hypogammaglobulinemia immunodeficiency immunology lymphohistiocytosis macrophage
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... versus DIL • ... - Cytopenia: Common ... of SLE • Evolution
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... to 1:1 F:M • Clinical ... , SCLE-DIL (terbinafine ... Discontinuation of causal ... of SLE • Evolution
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... , SCLE-DIL (terbinafine ... Cytopenia - Less common ... • Evolution: ... diagnosis #treatment #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... von Willebrand syndrome ... • Lupus anticoagulant ... defects in the common ... discern these causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... erythematosus [SLE ... #Diagnosis #Management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... 100 to 300 mg/dL ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rheumatic pain Clinical ... Rule out other causes ... Rheumatology #diagnosis #management ... #Dermatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
clinical manifestation ... Large vessels (aorta ... such as: • SLE ... • RA - Most common ... rheumatology #diagnosis #management
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