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management rheumatology lupus druginduced summary treatment algorithm comparison complications dil erythematosus hemophagocytic hlh lymphohistiocytosis polychondritis relapsing sicklecell systemic table
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Clinical Manifestations ... Management #Diagnosis ... #Workup #Algorithm ... #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Manifestations: ... • Immunologic Workup ... • Evolution:
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... life-threatening manifestations ... inhibitors under evaluation
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #treatment
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... manifestation) ... Large vessels (aorta ... such as: • SLE ... : • Clinical tests
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