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diagnosis rheumatology pain sle algorithm approach central classification comparison dermatologic druginduced erythematosus gap globulin gpa granulomatosis maculopapular management msk oncology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... on erythematous base ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... #rashes #differential
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
), RA, crystal disease ... spondyloarthropathies, lupus ... #rheumatology # ... approach #workup ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... : • Joint pain ... arthropathy • 90% joints ... vein thrombosis Hematologic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... NPSLE rare, Malar rash ... • Immunologic Workup ... • Immunologic Workup ... : Chronic disease
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... Maculopapular rash ... reticularis Differential ... • Giant cell arteritis ... Polyangiitis #GPA #dermatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
differentiated based ... assessed for Lyme disease ... have a broader differential ... require emergent evaluation ... #Diagnosis #Dermatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Rash: multiple ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... vesicular eruption - Joints ... mucositis - Rash ... such as systemic lupus
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... gastric tumors • Hematology ... #diagnosis #hematology
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