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hematology anemia differential algorithm causes macrocytosis management rbc aafp aplastic atlas bloodcell cobalamin elevatedmcv fat fatrbc folate folicacid homocysteine mcv
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... Spherocytosis, G6PD, PK, HbC ... Infections Macrocytic ... , B12 deficiency ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... • Drugs Oval Macrocytes ... Neutrophils - Low RBC ... • Dietary Deficiency ... and Folate Deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... (sometimes) Macrocytic ... RBC: Vitamin B12 ... #differential #diagnosis ... #hematology #microscopy
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... of macrocytic anemia ... (RBC = red blood ... #Diagnosis #Macrocytosis ... #Macrocytic #Anemia
FAT RBC Mnemonic for Causes of Macrocytic Anemia (MCV > 100) F - Folate (Fetus) and B12 Deficiency
for Causes of Macrocytic ... Folate (Fetus) and B12 ... Deficiency - Impairs ... Mnemonic #Causes #Macrocytic ... #Diagnosis #Hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... : • Worsening macrocytic ... related to IBD, celiac ... total body stores Evaluation ... • Labs: - CBC
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... article/S0002-9343(12 ... tachycardia or fever ... count on initial evaluation ... #CBC #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... , GATA2 deficiency ... , CTLA4 deficiency ... #diagnosis #management
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