10 results
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... • Autoimmune diseases ... tachycardia or fever ... count on initial evaluation ... #CBC #hematology
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
uncharacterized fevers ... Consider BCx, CSF evaluation ... #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness ... #Ddxof
Algorithm for the Evaluation of Kawasaki and Incomplete Kawasaki Disease:
Diagnosis
* Fever >5d
* Criteria (4/5)
  -
Algorithm for the Evaluation ... : Diagnosis * ... Fever >5d * Criteria ... #Peds #Pediatrics ... Workup #Algorithm #Ddxof
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... Anemia (common) ... flank pain (CLOT COLIC ... night sweats, fever ... with contrast Evaluation
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
related to IBD, celiac ... disease, other ... total body stores Evaluation ... hypersegmented neutrophils ... consider other diagnosis
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Evaluation of suspected ... incomplete Kawasaki Disease ... old on day ≥7 of fever ... Albumin ≤3.0 g/dL, anemia ... #Diagnosis #Peds
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... Leukemia): • Neutrophils ... Headaches, bone pain, fever ... Leukemia): • Neutrophils ... #Oncology #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema • NXG • Neutrophilic ... (-) hemolytic anemia ... Sneddon-Wilkinson disease ... #Differential #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... -95% of cases) Classification ... lymph node biopsy (diagnostic ... number of sites of disease ... #classification
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
risk of clonal evolution ... median age at diagnosis ... tolerate anemia ... Functional defects in neutrophils ... #algorithm #hematology