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hematology differential oncology abdominal algorithm cll compared comparison erythemas gap gastroenterology globulin lymphocytic mds myelodysplasia myelodysplastic pain protein proteingap syndromes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia ... Myelofibrosis Infectious ... disorders • Celiac ... #Hematology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Diagnosis Framework ... have had prior evaluations ... Red Flags: • Fever ... thrombus • Splenic infarction ... • Lymphoma/Leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> AML: Blast crises ... Headaches, bone pain, fever ... #Hematology #Oncology ... #Diagnosis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... known as rat bite fever ... or Haverhill fever ... #differential #diagnosis ... #dermatology #compared
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphadenopathy • Fevers ... weeks without infection ... #CLL #Chronic ... #diagnosis #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Include: • Viral infections ... : Lymphoma, Leukemia ... #differential #diagnosis
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