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diagnosis differential algorithm approach classification cobalamin elevatedmcv falls gap geriatrics globulin macrocytic macrocytosis management mds myelodysplasia myelodysplastic neurology nutrition oncology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
chronic kidney disease ... - Vitamin B12 ... Probable bone marrow disorder ... Underproduction #Algorithm #hematology ... #differential #workup
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... • Small Bowel Disorder ... and Folate Deficiency ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
• B12/Folate ... Deficiency • Aplastic ... of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... changes), high MCV anemia ... - Bone marrow evaluation ... #Workup #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... dysfunction, and/or disorders ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Syndromes #diagnosis #hematology
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
Evaluation of Recurrent ... embolism - Severe anemia ... e.g., diabetic, B12 ... deficiency) ... #Differential #Evaluation
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia
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