11 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... and Management ... of Sickle Cell Crises ... #Hematology #SickleCell ... Workup #Algorithm #Ddxof
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
immunosuppressive meds ... Anticoagulation (case ... by case) • Surgery ... Syndrome #Treatment #management ... #pharmacology #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Positive in 60-80% of cases ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... Diagnosis and Management ... , Cough • +/-Nausea ... , vomiting, diarrhea ... KD #vasculitis #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... normal in mild cases ... Avoid meds that ... #treatment #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Infectious diarrhea ... and M panel Management ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... tongue), abd pain, diarrhea ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... cutaneous eruptions, diarrhea ... Transfusion #diagnosis #management ... #hematology #reactions