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diagnosis management rheumatology lupus druginduced summary treatment anemia comparison differential erythematosus hemophagocytic hlh hospitalization lymphohistiocytosis pseudoanemia systemic table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
, SCLE-DIL (terbinafine ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
versus DIL • ... • Immunologic Workup ... Positive in 60-80% of cases ... • Evolution: ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Fibrinogen level, ↑ sIL ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... inhibitors under evaluation
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... • Immunologic Workup ... Discontinuation of causal ... • Evolution: ... #rheumatology #
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
Hospitalization - Pathophysiology ... day was due to admission ... phlebotomy/ blood work ... during clinical evaluations ... #pathophysiology
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