13 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... flow cytometry — GP ... cytometry— GP lb ... qualitative defects of GP ... #disorders #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Vasculitides, IBD ... , Celiac disease ... Diagnosis #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... - Bone marrow evaluation ... disorder is suspected ... Diagnosis #Causes #Workup ... #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
due to a lack of GP ... Ib/IX/V [vWF receptor ... due to a lack of GP ... MYH9-Related Disorder ... differential #diagnosis #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Diagnosis and Workup ... - Rule out celiac ... Pelvic Floor Disorder ... and Hepatology ... #gastroenterology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... administration, evaluation ... The appropriate evaluations ... Differential #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... intravascular hemolysis Platelet ... and decreased platelet ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... RA, Sjogren's, GPA ... deficiency Work ... Algorithm #Causes #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Disorders • Nutritional ... Workup: • Complete ... Syndromes #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology