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diagnosis differential lupus management druginduced hematology algorithm comparison dermatology dil erythematosus gap globulin hearing loss otolaryngology otology petechiae petechial platelet
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... - Bone marrow evaluation ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
- CRP: Usually normal ... • Immunologic Workup ... Positive in 60-80% of cases ... • Evolution: ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... • Evolution: ... comparison #table #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... deficiency - Abnormal ... Vasculitis - Collagen disorders ... deficiency Work ... #dermatology #physicalexam
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
The evaluation should ... include a: • Neurologic ... tympanic membrane • Neurologic ... Rinne Test: • Normal ... Mitochondrial disorders
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... affects the skin, neurologic ... fluid (CSF) is abnormal ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Connective tissue disorders ... chain assay • An abnormal ... light chain • Normal
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... DrugInduced #Lupus #DIL #rheumatology
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