9 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Drugs, Unknown cause ... inhibitors under evaluation ... #management #treatment ... #summary #rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Summary Causes ... Muscle swelling - Fever ... of underlying disease ... #Management #causes
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... affects the skin, neurologic ... rhinitis/sinusitis, saddle ... tract, and often causes ... #Rheumatology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... irrigation • Management ... Kidney stones caused ... • Liddle syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Shock, Autoimmune disease ... Immunosuppressive agents, Renal ... the underlying cause ... #management #neurology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... , DIC, hypoTN, renal ... Causes purpura & ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... , DIC, hypoTN, renal ... Causes purpura & ... #Transfusions #diagnosis ... #management #hematology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
, add other BP meds ... • Refractory cases ... #Crisis #rheumatology ... #nephrology #diagnosis ... #management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Nonspecific symptoms: Fever ... Heart failure • Renal ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management