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diagnosis management hematology mds 1 anemia aplastic bleeding boweldisease cdi cdiff cell chronic classification cll clostridioides clostridium difficile disorders evidence
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... diagnosis and risk-stratification ... • Risks: infection ... only curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... factor (GCSF) treatments ... marrow studies Treatment ... and reducing the risk ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Risk Factors: ... • History of EBV ... Treatment • Early ... classification #hematology #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
PTLD) Definition: Lymphoid ... Epidemiology: Lymphoma ... immunocompetent population Risk ... liver>kidney), EBV ... Lymphoproliferative #Disorders #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
to large cell lymphoma ... transformation) Treatment ... chemotherapy for low-risk ... AIHA, PRCA) • Treatment ... Lymphocytic #Leukemia #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... Parvovirus B19 - EBV ... • Hypocellular myelodysplastic ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Acute Diarrhea (>3 BM ... immunocompromised, IBD) • ↑Risk ... Lowest Risk: Tetracyclines ... IDSA 2021 CDI Treatment ... infectiousdiseases #IDSA #gastroenterology
Thiopurines in IBD Indications: • Steroid-sparing agents indicated for maintenance of remission in UC and CD •
Lymphomas are ↑ ... HSTC lymphoma (potentially ... EBV seroconversion ... adults already EBV ... BowelDisease #Management #Treatment
Evidence for Treatment of Acute Esophageal Variceal Bleeding • Octreotide (PMID: 11870374) - Endoscopic banding +
Evidence for Treatment ... without increased risk ... varices #management #ebm ... #evidence #gastroenterology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Bone marrow Treatment ... plasmacytoma carries a risk ... involvement - higher risk ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology
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