64 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... calcinosis • Pulmonary ... interstitial lung disease ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... disease, Pulmonary ... disease (~93-95% ... ), Pulmonary hypertension ... BCM_InternalMed #Systemic
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... solid cancers • Systemic ... hepatitis • Pulmonary ... management #treatment #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SSc: systemic sclerosis ... arthritis SLE : systemic ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
and Primary Causes ... Cholestatic liver disease ... syndrome Psychiatric Disease ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Systolic dysfunction ... pulmonary disease ... multifactorial mechanisms Hematologic ... disorders, lenectomy Systemic ... #Differential #Causes
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm
Pulmonary Arterial Hypertension
 • Idiopathic
 • Associated with:
Causes of Pulmonary ... Diagnosis Algorithm Pulmonary ... Dysfunction: • Systolic ... Miscellaneous: • Hematologic ... Diagnosis #Algorithm #Causes
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... Rash - Differential ... • Bullous systemic ... Vesiculobullous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
vasculitis which causes ... ulceration of the skin ... a number of systemic ... diseases, it is ... Clinical #Photo #Dermatology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... (cutaneous or systemic ... early localized disease ... multiforme • Acute systemic ... Erythemas #comparison #table