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management differential syndromes barre bee caudaequina dermatology disorders encephalopathy gbs guillain leukemia leukostasis lymphoproliferative lysis mds ms multiple myelitis myelodysplasia
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... conjunction with symptoms ... neuropathy (LHON) plus MRI ... consistent with MS ... #neurology #noninflammatory
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... resonance imaging [MRI ... objective evidence of neurologic ... #management #neurology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... , unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... have fever - ACS ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Neurological symptoms ... the underlying cause ... with AEDs until cause ... #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... skin that are caused ... #diagnosis #hematology ... #oncology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Bilateral signs ... and/or symptoms ... Transverse Myelitis Diagnosis ... #management #neurology
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