8 results
hematology anemia hemophagocytic hlh lymphohistiocytosis oncology brain clinical crypto cryptococcal differential fungal mds meningitis mri mycoses myelitis myelodysplasia myelodysplastic neurology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... : • Recurrent infections ... #Anemia #diagnosis ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... anemia Treatment ... oncology #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... can mimic common infections ... Ferritin >500 ng/mL ... : • Infection ... #management #treatment
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Histoplasmosis Diagnosis ... transplantation • MCC ... MC: CNS CSF: • ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Bilateral signs ... • Nutritional Deficiency ... Transverse Myelitis Treatment ... #management #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... or folic acid deficiency ... • Parvovirus infection ... • Copper deficiency ... Myelodysplastic #Syndromes #diagnosis
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... organism (soap bubble sign ... Standard treatment ... )but severe K+ deficiency ... is typically 20 ml
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