19 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... +/- diarrhea Diagnosis ... #management #treatment ... #microbiology #infectiousdiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... Ferritin >500 ng/mL ... : • Infection ... #management #treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Anticardiolipin antibodies (aCL ... to be present Treatment ... target to 3-4 • DOACs ... #management #anticoagulation
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection ... #management #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... aplastic anemia Treatment ... oncology #hematology #diagnosis ... #management
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... Nasal polyps and signs ... parenchyma Diagnosis ... α1-antitrypsin deficiency ... mycobacteria Treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Preeclampsia, Eclampsia, Infection ... : • Infection, ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... or folic acid deficiency ... • Parvovirus infection ... • Copper deficiency ... #diagnosis #hematology