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hematology management hodgkins leukemia lymphoma apml chronic classification comparison differential differentiation fungal hemophagocytic hlh infections infectiousdiseases lymphocytic lymphohistiocytosis mastoiditis mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Differential Diagnosis ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... : >3 symptoms, or ... #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... Low or absent NK cell ... Ferritin >500 ng/mL ... management #treatment #hematology
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
cells) Stage 4: Cell ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... low red blood cell ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... classical HL (MCHL ... lymph node biopsy (diagnostic ... #oncology #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lymphoma Pathophysiology ... and the systemic symptoms ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... transplantation • MCC ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... becomes a yeast cell
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