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differential hematology management oncology pathophysiology vasculitis algorithm arthritis autoimmune caudaequina cecs chronic chronicexertional classification cll compartmentsyndrome disorders eosinophil eosinophilia heon
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... at the time of diagnosis ... anterior/posterior MSK ... #Sarcoidosis #Diagnosis ... #Management #Signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... #diagnosis #hematology
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Exertional Compartment Syndrome ... (CECS) • Diagnosis ... activity that causes ... #signs #symptoms ... #msk
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... #MSK #rheumatology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... ) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
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